Pharmaceutical-Biotech Sector's Increasing Demand Drives SAFC High Potency APIs CMO Expansion Project in Madison

---

Researched by Industrialinfo.com (Industrial Information Resources, Incorporated; Houston, Texas). SAFC (Madison, Wisconsin), the custom chemical manufacturing division of Sigma-Aldrich Corporation (NYSE:SIAL) (Saint Louis, Missouri), is in the midst of an expansion project that will more than double its existing 23,500 square-foot facility. The investment is in response to the growing demand for custom chemical manufacturing capacity for high potency advanced pharmaceutical ingredients (APIs), which includes category III and IV compounds.

SAFC acquired the Madison plant last year, which was formerly owned by Tetrionics. As reported in July 2004 in the Industrialinfo.com Pharmaceutical Tracker - Online Database, Tetrionics had already made plans for the expansion, having hired Strang (Madison, Wisconsin) to design the project, when the company changed hands. Vogel Brothers (Madison, Wisconsin), the project's construction manager, expects to complete the 38,000 square-foot expansion early next year.

The SAFC site is equipped for the development and manufacturing of highly potent/cytotoxic APIs. It is one of a fairly limited number of premiere HPAPI contract manufacturing facilities in the world and is fully certified for compound handling. Services performed include those development projects that require chemistry that is difficult to handle because of its physical and biological properties or because the synthetic process is extremely long and complex requiring experienced personnel that understands the complexities associated with such processes.

A definite trend within the industry is that rather than invest in-house, initially or long-term, companies are turning to others that offer state-of-the-art process and production technology, such as the SAFC plant. As a result, the contract manufacturing organization (CMO) segment as a whole is experiencing steadily increasing demand.

Trends such as this and other factors that drive capital spending are found in the essential 2005 North American Pharmaceutical-Biotech Forecast, a wealth of important information gathered together into one vital reference point. Features include statistical analysis of project spending (updated quarterly), the industry's top earners, plant starts/closures and Industrialinfo.com's exclusive 2005 North America Pharma Industry Wall Map (covering plants that are operational as well as those under development).

View Plant Profile - 1063048
View Project Report - 19001317

Industrial Information Resources (IIR) is a Marketing Information Service company that has been in business for over 22 years. IIR is respected as a leader in providing comprehensive market information pertaining to the industrial processing, heavy manufacturing and energy related industries throughout the world.