Cambrex Completes Expansion of Massachusetts Biologics Facility and Considers other Sites for $2 Million Capital Investment in Pharmaceuticals Capacity

---

Industrialinfo.com (Industrial Information Resources, Incorporated; Houston, Texas). Earlier this summer, Cambrex (NYSE: CBM) (East Rutherford, New Jersey) announced the completion of an expansion at its biologics production plant in Hopkinton, Massachusetts. As first reported by Industrialinfo.com in September of 2002, nearly $8 million was invested to beef up CGMP contract biological production capacity.

The plant in Hopkinton is operated by Cambrex’s subsidiary, Cambrex Bio Science Hopkinton Incorporated and offers contract manufacturing of bulk biopharmaceuticals, with a range of capacities, from 40 to 2,800 liters. The manufacturing capacity expansion included the installation of a 2,800-liter production fermentor, a 280-liter feed tank, a continuous-flow centrifuge, a high-pressure homogenizer, and 500 to 2,500-liter process vessels for recovery, extraction, and refold operations.

Cambrex has additional biopharmaceuticals contract manufacturing capacity through another subsidiary in Maryland, Cambrex Bio Science Baltimore Incorporated. Both of the Bio Science sites provide pre-clinical, Phase I to III, and commercial-scale production of biopharmaceutical vaccines and therapeutics. Projects are taken from process development through manufacturing and long-term supply. Ancillary services include formulation development, stability studies, process and analytical validation, and regulatory support.

The company is now in the process of selecting a site for a $2 million pharmaceutical manufacturing expansion. The project would include the addition of $1.8 million in equipment and approximately $200,000 for renovation of the facility to provide compounding, drying, and milling of commercial quantities of active pharmaceutical ingredient compounds. Cambrex sites in Iowa, New Jersey, Italy, and Sweden are under consideration for the expansion project.

For more information on life science companies and projects, click the following link to view Industrialinfo.com's exclusive Pharma Tracker with our Pharmaceutical-Biotech Database featuring comprehensive plant profiles and project reports and be sure to check out the 2004 North American Pharmaceutical-Biotech Forecast (featuring 3Q04 update).